Joint Position Statement from the International Society of Prenatal Diagnosis (ISPD), the Society of Maternal Fetal Medicine (SMFM) and the Perinatal Quality Foundation (PQF) on the use of genome-wide sequencing for fetal diagnosis
International Society for Prenatal Diagnosis, SMFM, Perinatal Quality Foundation2018
International Society for Prenatal Diagnosis, SMFM, Perinatal Quality Foundation — 2018
This Joint ISPD, SMFM, and PQF Position Statement reflects the data and technology available for consensus review at the time of its preparation in November 2017. The authors recognize that genomic technologies are developing rapidly and that scientific and clinical knowledge about their use for prenatal diagnostic evaluation for fetal disease and malformations is still incomplete and constantly changing. Widespread health professional education is required to enable appropriate implementation and delivery of clinically effective and beneficial fetal sequencing. Clinical and translational research in this area is needed, and its funding should be prioritized. The results of such studies are likely to inform further refinement of this statement, which will require regular review and modification to take into account the evolving scientific, clinical, ethical, and societal context.
This Joint ISPD, SMFM, and PQF Position Statement reflects the data and technology available for consensus review at the time of its preparation in November 2017. The authors recognize that genomic technologies are developing rapidly and that scientific and clinical knowledge about their use for prenatal diagnostic evaluation for fetal disease and malformations is still incomplete and constantly changing. Widespread health professional education is required to enable appropriate implementation and delivery of clinically effective and beneficial fetal sequencing. Clinical and translational research in this area is needed, and its funding should be prioritized. The results of such studies are likely to inform further refinement of this statement, which will require regular review and modification to take into account the evolving scientific, clinical, ethical, and societal context.